GC36877
PF 05089771
Also known as 4-[2-(5-amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-(1,3-thiazol-4-yl)benzenesulfonamide
PF 05089771 is a potent, orally active and selective arylsulfonamide Nav1·7 inhibitor, with IC50 values of 11 nM, 12 nM, 13 nM, 171 nM and 8 nM for hNav1·7, cynNav1·7, dogNav1·7,ratNav1·7, and musNav1·7, respectively
ChemicalCAS1235403-62-9MW500.35FormulaC18H12Cl2FN5O3S2
- CAS number
- 1235403-62-9
- Molecular weight
- 500.35
- Formula
- C18H12Cl2FN5O3S2
- Solubility
- DMSO： ≥ 34 mg/mL (67·95 mM)
- InChIKey
- ZYSCOUXLBXGGIM-UHFFFAOYSA-N
- Catalogue number
- GC36877
- Brand
- GLPBIO
Computed properties PubChem CID 46840946 · XLogP 4.3 · TPSA 160 Ų · H-bond donors 3
- XLogP
- 4.3
- TPSA
- 160 Ų
- H-bond donors
- 3
- H-bond acceptors
- 9
- Rotatable bonds
- 6
- Heavy atoms
- 31
SMILES C1=CC(=C(C=C1Cl)C2=C(NN=C2)N)OC3=CC(=C(C=C3Cl)S(=O)(=O)NC4=CSC=N4)F
Computed descriptors from PubChem (CID 46840946), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il