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Chemical structure of PF 06465469

GC17630

PF 06465469

Also known as 3-[4-amino-1-[(3R)-1-prop-2-enoylpiperidin-3-yl]pyrazolo[3,4-d]pyrimidin-3-yl]-N-(3-methyl-4-propan-2-ylphenyl)benzamide

inhibitor of interleukin-2 inducible T cell kinase (ITK) and Bruton's tyrosine kinase (BTK)

ChemicalCAS1407966-77-1MW523.63FormulaC30H33N7O2
CAS number
1407966-77-1
Molecular weight
523.63
Formula
C30H33N7O2
Solubility
＜2·62mg/ml in DMSO
InChIKey
CGJVMKJGKFEHTL-HSZRJFAPSA-N
Catalogue number
GC17630
Brand
GLPBIO
Computed properties PubChem CID 71450146 · XLogP 4.4 · TPSA 119 Ų · H-bond donors 2
XLogP
4.4
TPSA
119 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
6
Heavy atoms
39

SMILES CC1=C(C=CC(=C1)NC(=O)C2=CC=CC(=C2)C3=NN(C4=NC=NC(=C34)N)[C@@H]5CCCN(C5)C(=O)C=C)C(C)C

Computed descriptors from PubChem (CID 71450146), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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