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Chemical structure of Osimertinib dimesylate

GC36819

Osimertinib dimesylate

Also known as N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide;methanesulfonic acid

Osimertinib dimesylate (AZD-9291 dimesylate) is an irreversible and mutant selective EGFR inhibitor with IC50s of 12 and 1 nM against EGFRL858R and EGFRL858R/T790M, respectively

ChemicalCAS2070014-82-1MW691.82FormulaC30H41N7O8S2
CAS number
2070014-82-1
Molecular weight
691.82
Formula
C30H41N7O8S2
Solubility
DMSO： 0·4 mg/mL (0·58 mM and warming)
InChIKey
RPUCCTLBBCSFEX-UHFFFAOYSA-N
Catalogue number
GC36819
Brand
GLPBIO
Computed properties PubChem CID 92044416 · TPSA 213 Ų · H-bond donors 4 · H-bond acceptors 13
TPSA
213 Ų
H-bond donors
4
H-bond acceptors
13
Rotatable bonds
10
Heavy atoms
47

SMILES CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC.CS(=O)(=O)O.CS(=O)(=O)O

Computed descriptors from PubChem (CID 92044416), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.