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Chemical structure of NVS-CRF38

GC36787

NVS-CRF38

Also known as 7-(3,5-dimethyl-1,2,4-triazol-1-yl)-3-(4-methoxy-2-methylphenyl)-2,6-dimethylpyrazolo[5,1-b][1,3]oxazole

NVS-CRF38 is a novel corticotropin-releasing factor receptor 1 (CRF1) antagonist with low water solubility

ChemicalCAS1207258-55-6MW351.4FormulaC19H21N5O2
CAS number
1207258-55-6
Molecular weight
351.4
Formula
C19H21N5O2
Solubility
Soluble in DMSO
InChIKey
MEICIUGVENCLKP-UHFFFAOYSA-N
Catalogue number
GC36787
Brand
GLPBIO
Computed properties PubChem CID 44816934 · XLogP 3.8 · TPSA 70.4 Ų · H-bond donors 0
XLogP
3.8
TPSA
70.4 Ų
H-bond donors
0
H-bond acceptors
5
Rotatable bonds
3
Heavy atoms
26

SMILES CC1=C(C=CC(=C1)OC)C2=C(OC3=C(C(=NN23)C)N4C(=NC(=N4)C)C)C

Computed descriptors from PubChem (CID 44816934), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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