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Chemical structure of NaV1·7 inhibitor-1

GC36698

NaV1·7 inhibitor-1

Also known as 5-cyclopropyl-N-cyclopropylsulfonyl-2-fluoro-4-[(6-methylspiro[2.5]octan-6-yl)methoxy]benzamide

NaV1·7 inhibitor-1 is an efficacious voltage-gated sodium channel (NaV) 1·7 inhibitor with an IC50 of 0·6 nM for hNaV1·7, exhibits 80-fold selectivity versus hNaV1·5

ChemicalCAS1494585-79-3MW435.55FormulaC23H30FNO4S
CAS number
1494585-79-3
Molecular weight
435.55
Formula
C23H30FNO4S
Solubility
DMSO : 100 mg/mL (229·59 mM; ultrasonic and warming and heat to 60°C)
InChIKey
GFDXIUXAFNREKM-UHFFFAOYSA-N
Catalogue number
GC36698
Brand
GLPBIO
Computed properties PubChem CID 90026208 · XLogP 5.5 · TPSA 80.9 Ų · H-bond donors 1
XLogP
5.5
TPSA
80.9 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
7
Heavy atoms
30

SMILES CC1(CCC2(CC1)CC2)COC3=CC(=C(C=C3C4CC4)C(=O)NS(=O)(=O)C5CC5)F

Computed descriptors from PubChem (CID 90026208), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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