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Chemical structure of Mutant IDH1 inhibitor

GC36665

Mutant IDH1 inhibitor

Also known as (4S)-3-[2-[[(1S)-1-[4-[(4-acetylpiperazin-1-yl)methyl]phenyl]ethyl]amino]pyrimidin-4-yl]-4-propan-2-yl-1,3-oxazolidin-2-one

Mutant IDH1 inhibitor is a potent mutant IDH1 R132H inhibitor with IC50 of ＜ 72 nM

ChemicalCAS1429180-08-4MW466.58FormulaC25H34N6O3
CAS number
1429180-08-4
Molecular weight
466.58
Formula
C25H34N6O3
Solubility
DMSO： ≥ 34 mg/mL (72·87 mM)
InChIKey
BEWLUEOYYPKPQL-PGRDOPGGSA-N
Catalogue number
GC36665
Brand
GLPBIO
Computed properties PubChem CID 71542482 · XLogP 2.8 · TPSA 90.9 Ų · H-bond donors 1
XLogP
2.8
TPSA
90.9 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
7
Heavy atoms
34

SMILES C[C@@H](C1=CC=C(C=C1)CN2CCN(CC2)C(=O)C)NC3=NC=CC(=N3)N4[C@H](COC4=O)C(C)C

Computed descriptors from PubChem (CID 71542482), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.