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Chemical structure of Mutant IDH1-IN-2

GC32966

Mutant IDH1-IN-2

Also known as (4S)-3-[2-[[(1S)-1-[4-[(4,4-difluoropiperidin-1-yl)methyl]phenyl]ethyl]amino]pyrimidin-4-yl]-4-propan-2-yl-1,3-oxazolidin-2-one

Mutant IDH1-IN-2 is a inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with IC50 of in LS-MS biochemical assay, IC50 of 16·6 nM in Fluorescence biochemical assay

ChemicalCAS1429176-69-1MW459.53FormulaC24H31F2N5O2
CAS number
1429176-69-1
Molecular weight
459.53
Formula
C24H31F2N5O2
Solubility
DMSO ： 50 mg/mL (108·81 mM);Water ： ＜ 0·1 mg/mL (insoluble)
InChIKey
OCZCXJFDMAWAIM-FXAWDEMLSA-N
Catalogue number
GC32966
Brand
GLPBIO
Computed properties PubChem CID 71515481 · XLogP 4.7 · TPSA 70.6 Ų · H-bond donors 1
XLogP
4.7
TPSA
70.6 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
7
Heavy atoms
33

SMILES C[C@@H](C1=CC=C(C=C1)CN2CCC(CC2)(F)F)NC3=NC=CC(=N3)N4[C@H](COC4=O)C(C)C

Computed descriptors from PubChem (CID 71515481), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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