Loading...
Chemical structure of MI-1061

GC36605

MI-1061

MI-1061 is a potent, orally bioavailable, and chemically stable MDM2 (MDM2-p53 interaction) inhibitor (IC50=4·4 nM; Ki=0·16 nM)· MI-1061 potently activates p53 and induces apoptosis in the SJSA-1 xenograft tumor tissue in mice· Anti-tumor activity

ChemicalCAS1410737-34-6MW582.45FormulaC30H26Cl2FN3O4
CAS number
1410737-34-6
Molecular weight
582.45
Formula
C30H26Cl2FN3O4
Solubility
DMSO: 300 mg/mL (515·07 mM)
InChIKey
BIDSEXPFIMKDMF-LOLKONATSA-N
Catalogue number
GC36605
Brand
GLPBIO
Computed properties PubChem CID 70677271 · XLogP 2.9 · TPSA 108 Ų · H-bond donors 4
XLogP
2.9
TPSA
108 Ų
H-bond donors
4
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
40

SMILES C1CCC2(CC1)[C@@]3([C@H]([C@@H](N2)C(=O)NC4=CC=C(C=C4)C(=O)O)C5=C(C(=CC=C5)Cl)F)C6=C(C=C(C=C6)Cl)NC3=O

Computed descriptors from PubChem (CID 70677271), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.