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Chemical structure of Mavorixafor trihydrochloride

GC36550

Mavorixafor trihydrochloride

Also known as N'-(1H-benzimidazol-2-ylmethyl)-N'-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine;trihydrochloride

Mavorixafor trihydrochloride (AMD-070 trihydrochloride) is a potent, selective and orally available CXCR4 antagonist, with an IC50 value of 13 nM against CXCR4 125I-SDF binding, and also inhibits the replication of T-tropic HIV-1 (NL4·3 strain) in MT-4 cells and PBMCs with an IC50 of 1 and 9 nM, respectively

ChemicalCAS2309699-17-8MW458.86FormulaC21H30Cl3N5
CAS number
2309699-17-8
Molecular weight
458.86
Formula
C21H30Cl3N5
Solubility
DMSO： 6 mg/mL (13·08 mM)
InChIKey
FTHQTOSCZZCGHB-VLEZWVESSA-N
Catalogue number
GC36550
Brand
GLPBIO
Computed properties PubChem CID 78357868 · TPSA 70.8 Ų · H-bond donors 5 · H-bond acceptors 4
TPSA
70.8 Ų
H-bond donors
5
H-bond acceptors
4
Rotatable bonds
7
Heavy atoms
29

SMILES C1C[C@@H](C2=C(C1)C=CC=N2)N(CCCCN)CC3=NC4=CC=CC=C4N3.Cl.Cl.Cl

Computed descriptors from PubChem (CID 78357868), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.