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Chemical structure of Mavelertinib

GC61030

Mavelertinib

Also known as N-[(3R,4R)-4-fluoro-1-[6-[(3-methoxy-1-methylpyrazol-4-yl)amino]-9-methylpurin-2-yl]pyrrolidin-3-yl]prop-2-enamide

Mavelertinib is a selective, orally available and irreversible EGFR tyrosine kinase inhibitor (EGFR TKI), with IC50s of 5, 4, 12 and 3 nM for Del, L858R, and double mutants T790M/L858R and T790M/Del, respectively· Mavelertinib can be used for the research of non-small-cell lung cancer (NSCLC)

ChemicalCAS1776112-90-3MW415.42FormulaC18H22FN9O2
CAS number
1776112-90-3
Molecular weight
415.42
Formula
C18H22FN9O2
InChIKey
JYIUNVOCEFIUIU-GHMZBOCLSA-N
Catalogue number
GC61030
Brand
GLPBIO
Computed properties PubChem CID 91668194 · XLogP 1.2 · TPSA 115 Ų · H-bond donors 2
XLogP
1.2
TPSA
115 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
6
Heavy atoms
30

SMILES CN1C=C(C(=N1)OC)NC2=C3C(=NC(=N2)N4C[C@H]([C@@H](C4)F)NC(=O)C=C)N(C=N3)C

Computed descriptors from PubChem (CID 91668194), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.