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Chemical structure of GSK3368715

GC36191

GSK3368715

Also known as N'-[[5-[4,4-bis(ethoxymethyl)cyclohexyl]-1H-pyrazol-4-yl]methyl]-N,N'-dimethylethane-1,2-diamine

GSK3368715 (EPZ019997) is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50=3·1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5·7 nM (PRMT6), 1·7 nM (PRMT8))· GSK3368715 (EPZ019997) produces a shift in arginine methylation states, alters exon usage, and has strong anti-cancer activity

ChemicalCAS1629013-22-4MW366.54FormulaC20H38N4O2
CAS number
1629013-22-4
Molecular weight
366.54
Formula
C20H38N4O2
Solubility
Soluble in DMSO
InChIKey
SPEGERVLTUWZPA-UHFFFAOYSA-N
Catalogue number
GC36191
Brand
GLPBIO
Computed properties PubChem CID 90462880 · XLogP 1.5 · TPSA 62.4 Ų · H-bond donors 2
XLogP
1.5
TPSA
62.4 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
12
Heavy atoms
26

SMILES CCOCC1(CCC(CC1)C2=C(C=NN2)CN(C)CCNC)COCC

Computed descriptors from PubChem (CID 90462880), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.