Loading...
Chemical structure of G150

GC36093

G150

Also known as 1-[9-(6-amino-3-pyridinyl)-6,7-dichloro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl]-2-hydroxyethanone

G150 is a highly selective human cyclic GMP-AMP synthase (h-cGAS) inhibitor with an IC50 of 10·2 nM

ChemicalCAS2369751-30-2MW391.25FormulaC18H16Cl2N4O2
CAS number
2369751-30-2
Molecular weight
391.25
Formula
C18H16Cl2N4O2
Solubility
DMSO： 125 mg/mL (319·49 mM)
InChIKey
VVUOUIPXYFIWLE-UHFFFAOYSA-N
Catalogue number
GC36093
Brand
GLPBIO
Computed properties PubChem CID 138393372 · XLogP 2.2 · TPSA 95.2 Ų · H-bond donors 3
XLogP
2.2
TPSA
95.2 Ų
H-bond donors
3
H-bond acceptors
4
Rotatable bonds
2
Heavy atoms
26

SMILES C1CN(CC2=C1NC3=C2C(=CC(=C3Cl)Cl)C4=CN=C(C=C4)N)C(=O)CO

Computed descriptors from PubChem (CID 138393372), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.