GC36038
FGTI-2734
Also known as N-[2-[4-cyano-2-fluoro-N-[(3-methylimidazol-4-yl)methyl]anilino]ethyl]-N-(cyclohexylmethyl)pyridine-2-sulfonamide
FGTI-2734 is a RAS C-terminal mimetic dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT-1) inhibitor with IC50s of 250 nM and 520 nM for FT and GGT-1, respectively· FGTI-2734 can prevent membrane localization of KRAS, hence solving KRAS resistance problem and thwarting mutant KRAS patient-derived pancreatic tumors
ChemicalCAS1247018-19-4MW510.63FormulaC26H31FN6O2S
- CAS number
- 1247018-19-4
- Molecular weight
- 510.63
- Formula
- C26H31FN6O2S
- Solubility
- DMSO： 50 mg/mL (97·92 mM)
- InChIKey
- BXNRVJLIEMQDOL-UHFFFAOYSA-N
- Catalogue number
- GC36038
- Brand
- GLPBIO
Computed properties PubChem CID 49783195 · XLogP 4 · TPSA 104 Ų · H-bond donors 0
- XLogP
- 4
- TPSA
- 104 Ų
- H-bond donors
- 0
- H-bond acceptors
- 8
- Rotatable bonds
- 10
- Heavy atoms
- 36
SMILES CN1C=NC=C1CN(CCN(CC2CCCCC2)S(=O)(=O)C3=CC=CC=N3)C4=C(C=C(C=C4)C#N)F
Computed descriptors from PubChem (CID 49783195), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il