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Chemical structure of E 2012

GC35921

E 2012

Also known as (3E)-1-[(1S)-1-(4-fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]methylidene]piperidin-2-one

E 2012 is a potent gamma (γ) secretase modulator without affecting Notch processing

ChemicalCAS870843-42-8MW419.49FormulaC25H26FN3O2
CAS number
870843-42-8
Molecular weight
419.49
Formula
C25H26FN3O2
Solubility
DMSO: ≥ 50 mg/mL (119·19 mM)
InChIKey
PUOAETJYKQITMO-LANLRWRYSA-N
Catalogue number
GC35921
Brand
GLPBIO
Computed properties PubChem CID 11560787 · XLogP 4.3 · TPSA 47.4 Ų · H-bond donors 0
XLogP
4.3
TPSA
47.4 Ų
H-bond donors
0
H-bond acceptors
4
Rotatable bonds
5
Heavy atoms
31

SMILES CC1=CN(C=N1)C2=C(C=C(C=C2)/C=C/3\CCCN(C3=O)[C@@H](C)C4=CC=C(C=C4)F)OC

Computed descriptors from PubChem (CID 11560787), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.