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Chemical structure of E 3810 dihydrochloride

GB40188

E 3810 dihydrochloride

Also listed as E 3810 dihydrochloride - AL 3810 dihydrochloride | Lucitanib

First-in-class dual VEGFR/FGFR tyrosine kinase inhibitor; E-3810 potently and selectively inhibited VEGFR1, -2, and -3 and FGFR-1 and -2 kinases in the nanomolar range; a potent antiangiogenic small molecule with a favorable pharmacokinetic profile and broad spectrum antitumor activity

ChemicalCAS2108875-91-6MW516.42FormulaC26H25N3O4·2HCl
CAS number
2108875-91-6
Molecular weight
516.42
Formula
C26H25N3O4·2HCl
InChIKey
GJYKJPXOPZOBBC-UHFFFAOYSA-N
Catalogue number
GB40188
Brand
GLPBIO
Computed properties PubChem CID 91826490 · TPSA 95.7 Ų · H-bond donors 4 · H-bond acceptors 6
TPSA
95.7 Ų
H-bond donors
4
H-bond acceptors
6
Rotatable bonds
7
Heavy atoms
35

SMILES CNC(=O)C1=CC=CC2=C1C=CC(=C2)OC3=C4C=C(C(=CC4=NC=C3)OCC5(CC5)N)OC.Cl.Cl

Computed descriptors from PubChem (CID 91826490), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.