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Chemical structure of Derazantinib Racemate

GC35839

Derazantinib Racemate

Also known as 6-(2-fluorophenyl)-N-[3-[2-(2-methoxyethylamino)ethyl]phenyl]-5,6-dihydrobenzo[h]quinazolin-2-amine

Derazantinib Racemate (ARQ-087 Racemate) is the racemate of Derazantinib· Derazantinib is an orally bioavailable, ATP competitive tyrosine kinase inhibitor; exhibits potent activity against FGFR1-3 chondrocytes with IC50s of 4·5, 1·8, and 4·5 nM, respectively

ChemicalCAS2309668-44-6MW468.57FormulaC29H29FN4O
CAS number
2309668-44-6
Molecular weight
468.57
Formula
C29H29FN4O
Solubility
Soluble in DMSO
InChIKey
KPJDVVCDVBFRMU-UHFFFAOYSA-N
Catalogue number
GC35839
Brand
GLPBIO
Computed properties PubChem CID 67541698 · XLogP 5.3 · TPSA 59.1 Ų · H-bond donors 2
XLogP
5.3
TPSA
59.1 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
9
Heavy atoms
35

SMILES COCCNCCC1=CC(=CC=C1)NC2=NC=C3CC(C4=CC=CC=C4C3=N2)C5=CC=CC=C5F

Computed descriptors from PubChem (CID 67541698), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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