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Chemical structure of Derazantinib

GC19399

Derazantinib

Also known as (6R)-6-(2-fluorophenyl)-N-[3-[2-(2-methoxyethylamino)ethyl]phenyl]-5,6-dihydrobenzo[h]quinazolin-2-amine

Derazantinib is a novel, ATP competitive, small molecule, multi-kinase inhibitor with IC50 of 1·8nM for FGFR2, and 4·5nM for FGFR1 and 3

ChemicalCAS1234356-69-4MW468.57FormulaC29H29FN4O
CAS number
1234356-69-4
Molecular weight
468.57
Formula
C29H29FN4O
Solubility
DMSO ： ≥ 100 mg/mL (213·42 mM)
InChIKey
KPJDVVCDVBFRMU-AREMUKBSSA-N
Catalogue number
GC19399
Brand
GLPBIO
Computed properties PubChem CID 46834118 · XLogP 5.3 · TPSA 59.1 Ų · H-bond donors 2
XLogP
5.3
TPSA
59.1 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
9
Heavy atoms
35

SMILES COCCNCCC1=CC(=CC=C1)NC2=NC=C3C[C@H](C4=CC=CC=C4C3=N2)C5=CC=CC=C5F

Computed descriptors from PubChem (CID 46834118), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.