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Chemical structure of CZC-25146 hydrochloride

GC35792

CZC-25146 hydrochloride

Also known as N-[2-[[5-fluoro-2-(2-methoxy-4-morpholin-4-ylanilino)pyrimidin-4-yl]amino]phenyl]methanesulfonamide;hydrochloride

CZC-25146 hydrochloride is a potent LRRK2 inhibitor with IC50 values of 4·76 nM and 6·87 nM for wild-type LRRK2 and G2019S LRRK2, respectively

ChemicalCAS1330003-04-7MW525FormulaC22H26ClFN6O4S
CAS number
1330003-04-7
Molecular weight
525
Formula
C22H26ClFN6O4S
Solubility
Soluble in DMSO
InChIKey
SKYQTYQDKAOHLP-UHFFFAOYSA-N
Catalogue number
GC35792
Brand
GLPBIO
Computed properties PubChem CID 72193880 · TPSA 126 Ų · H-bond donors 4 · H-bond acceptors 11
TPSA
126 Ų
H-bond donors
4
H-bond acceptors
11
Rotatable bonds
8
Heavy atoms
35

SMILES COC1=C(C=CC(=C1)N2CCOCC2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NS(=O)(=O)C)F.Cl

Computed descriptors from PubChem (CID 72193880), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.