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Chemical structure of CZC-8004 (CZC-00008004)

GC33351

CZC-8004 (CZC-00008004)

Also known as 2-N-[4-(aminomethyl)phenyl]-5-fluoro-4-N-phenylpyrimidine-2,4-diamine

CZC-8004 (CZC-00008004) (CZC-00008004), an aminopyrimidine, is a pan-kinase inhibitor· CZC-8004 (CZC-00008004) can bind a range of tyrosine kinases, including EGFR and VEGFR2 with IC50 values of 650 and 437 nM, respectively

ChemicalCAS916603-07-1MW309.34FormulaC17H16FN5
CAS number
916603-07-1
Molecular weight
309.34
Formula
C17H16FN5
Solubility
DMSO : 77·5 mg/mL (250·53 mM)
InChIKey
UKOHFWNBTUJMMN-UHFFFAOYSA-N
Catalogue number
GC33351
Brand
GLPBIO
Computed properties PubChem CID 15980598 · XLogP 2.9 · TPSA 75.9 Ų · H-bond donors 3
XLogP
2.9
TPSA
75.9 Ų
H-bond donors
3
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
23

SMILES C1=CC=C(C=C1)NC2=NC(=NC=C2F)NC3=CC=C(C=C3)CN

Computed descriptors from PubChem (CID 15980598), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.