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Chemical structure of Auristatin F

GC35430

Auristatin F

Also known as (2S)-2-[[(2R,3R)-3-[(2S)-1-[(3R,4S,5S)-4-[[(2S)-2-[[(2S)-2-(dimethylamino)-3-methylbutanoyl]amino]-3-methylbutanoyl]-methylamino]-3-methoxy-5-methylheptanoyl]pyrrolidin-2-yl]-3-methoxy-2-methylpropanoyl]amino]-3-phenylpropanoic acid

Auristatin F is a potent cytotoxin· Auristatin F, a potent microtubule inhibitor and vascular damaging agent (VDA), can be used in antibody-drug conjugates (ADC)

ChemicalCAS163768-50-1MW745.99FormulaC40H67N5O8
CAS number
163768-50-1
Molecular weight
745.99
Formula
C40H67N5O8
Solubility
DMSO： ≥ 56 mg/mL (75·07 mM)
InChIKey
LGNCNVVZCUVPOT-FUVGGWJZSA-N
Catalogue number
GC35430
Brand
GLPBIO
Computed properties PubChem CID 67472795 · XLogP 2.6 · TPSA 158 Ų · H-bond donors 3
XLogP
2.6
TPSA
158 Ų
H-bond donors
3
H-bond acceptors
9
Rotatable bonds
21
Heavy atoms
53

SMILES CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)O)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)N(C)C

Computed descriptors from PubChem (CID 67472795), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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