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Chemical structure of Auristatin E

GC35429

Auristatin E

Also known as (2S)-2-[[(2S)-2-(dimethylamino)-3-methylbutanoyl]amino]-N-[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-3-[[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-N,3-dimethylbutanamide

Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAE analog and cytotoxin in Antibody-drug conjugates· Auristatin E inhibits cell division by blocking the polymerisation of tubulin

ChemicalCAS160800-57-7MW732.01FormulaC40H69N5O7
CAS number
160800-57-7
Molecular weight
732.01
Formula
C40H69N5O7
Solubility
Soluble in DMSO
InChIKey
WOWDZACBATWTAU-FEFUEGSOSA-N
Catalogue number
GC35429
Brand
GLPBIO
Computed properties PubChem CID 11498622 · XLogP 4.5 · TPSA 141 Ų · H-bond donors 3
XLogP
4.5
TPSA
141 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
20
Heavy atoms
52

SMILES CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@H](C)[C@H](C2=CC=CC=C2)O)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)N(C)C

Computed descriptors from PubChem (CID 11498622), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.