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Chemical structure of Apilimod mesylate

GC35374

Apilimod mesylate

Also known as methanesulfonic acid;N-[(E)-(3-methylphenyl)methylideneamino]-6-morpholin-4-yl-2-(2-pyridin-2-ylethoxy)pyrimidin-4-amine

Apilimod (STA 5326) mesylate is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively

ChemicalCAS870087-36-8MW610.7FormulaC25H34N6O8S2
CAS number
870087-36-8
Molecular weight
610.7
Formula
C25H34N6O8S2
Solubility
Water: 100 mg/mL (163·75 mM); DMSO: 12·5 mg/mL (20·47 mM)
InChIKey
GAJWNIKZLYZYSY-OKUPSQOASA-N
Catalogue number
GC35374
Brand
GLPBIO
Computed properties PubChem CID 11527330 · TPSA 210 Ų · H-bond donors 3 · H-bond acceptors 14
TPSA
210 Ų
H-bond donors
3
H-bond acceptors
14
Rotatable bonds
8
Heavy atoms
41

SMILES CC1=CC(=CC=C1)/C=N/NC2=CC(=NC(=N2)OCCC3=CC=CC=N3)N4CCOCC4.CS(=O)(=O)O.CS(=O)(=O)O

Computed descriptors from PubChem (CID 11527330), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.