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Chemical structure of Apilimod

GC35373

Apilimod

Also known as N-[(E)-(3-methylphenyl)methylideneamino]-6-morpholin-4-yl-2-(2-pyridin-2-ylethoxy)pyrimidin-4-amine

Apilimod (STA 5326) is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively

ChemicalCAS541550-19-0MW418.49FormulaC23H26N6O2
CAS number
541550-19-0
Molecular weight
418.49
Formula
C23H26N6O2
Solubility
DMSO： ≥ 46 mg/mL (109·92 mM)
InChIKey
HSKAZIJJKRAJAV-KOEQRZSOSA-N
Catalogue number
GC35373
Brand
GLPBIO
Computed properties PubChem CID 10173277 · XLogP 3.8 · TPSA 84.8 Ų · H-bond donors 1
XLogP
3.8
TPSA
84.8 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
8
Heavy atoms
31

SMILES CC1=CC(=CC=C1)/C=N/NC2=CC(=NC(=N2)OCCC3=CC=CC=N3)N4CCOCC4

Computed descriptors from PubChem (CID 10173277), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.