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Chemical structure of AGN 205327

GC35267

AGN 205327

Also known as 2-[(E)-N-hydroxy-C-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)carbonimidoyl]-1H-indole-5-carboxylic acid

AGN 205327 is a potent synthetic RARs agonist with EC50 of 3766/734/32 nM for RARα/β/γ respectively; no inhibition on RXR

ChemicalCAS2070018-29-8MW390.47FormulaC24H26N2O3
CAS number
2070018-29-8
Molecular weight
390.47
Formula
C24H26N2O3
Solubility
Soluble in DMSO
InChIKey
CTYNDNYSDMIEPV-YYADALCUSA-N
Catalogue number
GC35267
Brand
GLPBIO
Computed properties PubChem CID 136284950 · XLogP 6.6 · TPSA 85.7 Ų · H-bond donors 3
XLogP
6.6
TPSA
85.7 Ų
H-bond donors
3
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
29

SMILES CC1(CCC(C2=C1C=CC(=C2)/C(=N\O)/C3=CC4=C(N3)C=CC(=C4)C(=O)O)(C)C)C

Computed descriptors from PubChem (CID 136284950), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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