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Chemical structure of JZP-430

GC34640

JZP-430

Also known as (4-morpholin-4-yl-1,2,5-thiadiazol-3-yl) N-cyclooctyl-N-methylcarbamate

JZP-430 is a potent, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) with an IC50 of 44 nM, exhibits ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL)

ChemicalCAS1672691-74-5MW354.47FormulaC16H26N4O3S
CAS number
1672691-74-5
Molecular weight
354.47
Formula
C16H26N4O3S
Solubility
DMSO ： 100 mg/mL (282·11 mM; Need ultrasonic)
InChIKey
WKSHMJCYWFOADB-UHFFFAOYSA-N
Catalogue number
GC34640
Brand
GLPBIO
Computed properties PubChem CID 121513897 · XLogP 3.4 · TPSA 96 Ų · H-bond donors 0
XLogP
3.4
TPSA
96 Ų
H-bond donors
0
H-bond acceptors
7
Rotatable bonds
4
Heavy atoms
24

SMILES CN(C1CCCCCCC1)C(=O)OC2=NSN=C2N3CCOCC3

Computed descriptors from PubChem (CID 121513897), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.