GC34628
IWP-O1
Also known as N-(5-phenyl-2-pyridinyl)-2-(5-phenyl-4-pyridin-4-yltriazol-1-yl)acetamide
IWP-O1 is a highly potent Porcupine (Porcn) inhibitor, with an EC50 of 80 pM in L-Wnt-STF cells· IWP-O1 prevents the secretion of Wnt proteins· IWP-O1 suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells
ChemicalCAS2074607-48-8MW432.48FormulaC26H20N6O
- CAS number
- 2074607-48-8
- Molecular weight
- 432.48
- Formula
- C26H20N6O
- Solubility
- DMSO ： 125 mg/mL (289·03 mM);Water ： ＜ 0·1 mg/mL (insoluble)
- InChIKey
- GYYDQHBKIHQHEB-UHFFFAOYSA-N
- Catalogue number
- GC34628
- Brand
- GLPBIO
Computed properties PubChem CID 134154594 · XLogP 3.8 · TPSA 85.6 Ų · H-bond donors 1
- XLogP
- 3.8
- TPSA
- 85.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 5
- Rotatable bonds
- 6
- Heavy atoms
- 33
SMILES C1=CC=C(C=C1)C2=CN=C(C=C2)NC(=O)CN3C(=C(N=N3)C4=CC=NC=C4)C5=CC=CC=C5
Computed descriptors from PubChem (CID 134154594), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il