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Chemical structure of Col003

GC34539

Col003

Also known as 5-benzyl-2-hydroxy-3-nitrobenzaldehyde

Col003 is a selective and potent inhibitor of?Hsp47 and competitively binds to the collagen binding site on Hsp47 (IC50=1·8 μM)

ChemicalCAS328565-16-8MW257.24FormulaC14H11NO4
CAS number
328565-16-8
Molecular weight
257.24
Formula
C14H11NO4
Solubility
DMSO: 25 mg/mL (97·19 mM)
InChIKey
RKJXVCLOGNLZOI-UHFFFAOYSA-N
Catalogue number
GC34539
Brand
GLPBIO
Computed properties PubChem CID 871077 · XLogP 3.3 · TPSA 83.1 Ų · H-bond donors 1
XLogP
3.3
TPSA
83.1 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
19

SMILES C1=CC=C(C=C1)CC2=CC(=C(C(=C2)[N+](=O)[O-])O)C=O

Computed descriptors from PubChem (CID 871077), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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