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Chemical structure of Colchicine

GC13261

Colchicine

Also known as N-(1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)acetamide

Colchicine, an orally active alkaloid, disrupts cytoskeletal function by inhibiting the polymerization of β-tubulin into microtubules, with an IC50 of 3 nM

ChemicalCAS64-86-8MW399.44FormulaC22H25NO6
CAS number
64-86-8
Molecular weight
399.44
Formula
C22H25NO6
Solubility
≥ 19·972 mg/mL in DMSO, ≥ 50·8 mg/mL in EtOH with gentle warming, ≥ 45·5 mg/mL in Water with gentle warming
InChIKey
IAKHMKGGTNLKSZ-UHFFFAOYSA-N
Catalogue number
GC13261
Brand
GLPBIO
Computed properties PubChem CID 2833 · XLogP 1 · TPSA 83.1 Ų · H-bond donors 1
XLogP
1
TPSA
83.1 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
29

SMILES CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC

Computed descriptors from PubChem (CID 2833), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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