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Chemical structure of CB-6644

GC34317

CB-6644

Also known as 5-chloro-2-ethoxy-4-fluoro-N-[4-[[3-(methoxymethyl)-1-oxo-6,7-dihydro-5H-pyrazolo[1,2-a][1,2]benzodiazepin-2-yl]amino]-2,2-dimethyl-4-oxobutyl]benzamide

CB-6644 is a selective inhibitor of RUVBL1/2 complex with anti-cancer activity· CB-6644 blocks the ATPase activity of RUVBL1/2 with an IC50 of 15 nM

ChemicalCAS2316817-88-4MW573.06FormulaC29H34ClFN4O5
CAS number
2316817-88-4
Molecular weight
573.06
Formula
C29H34ClFN4O5
Solubility
DMSO： 100 mg/mL (174·50 mM)
InChIKey
VYCOZEBCSAQCES-UHFFFAOYSA-N
Catalogue number
GC34317
Brand
GLPBIO
Computed properties PubChem CID 137333455 · XLogP 4.2 · TPSA 100 Ų · H-bond donors 2
XLogP
4.2
TPSA
100 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
10
Heavy atoms
40

SMILES CCOC1=CC(=C(C=C1C(=O)NCC(C)(C)CC(=O)NC2=C(N3CCCC4=CC=CC=C4N3C2=O)COC)Cl)F

Computed descriptors from PubChem (CID 137333455), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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