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Chemical structure of CB-839

GC15227

CB-839

Also known as N-[6-[4-[5-[(2-pyridin-2-ylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]pyridazin-3-yl]-2-[3-(trifluoromethoxy)phenyl]acetamide

Telaglenastat (CB-839) is a first-in-class, reversible and orally bioavailable glutaminase 1 (GLS1) inhibitor

ChemicalCAS1439399-58-2MW571.57FormulaC26H24F3N7O3S
CAS number
1439399-58-2
Molecular weight
571.57
Formula
C26H24F3N7O3S
Solubility
≥ 28·6mg/mL in DMSO
InChIKey
PRAAPINBUWJLGA-UHFFFAOYSA-N
Catalogue number
GC15227
Brand
GLPBIO
Computed properties PubChem CID 71577426 · XLogP 3.6 · TPSA 160 Ų · H-bond donors 2
XLogP
3.6
TPSA
160 Ų
H-bond donors
2
H-bond acceptors
12
Rotatable bonds
12
Heavy atoms
40

SMILES C1=CC=NC(=C1)CC(=O)NC2=NN=C(S2)CCCCC3=NN=C(C=C3)NC(=O)CC4=CC(=CC=C4)OC(F)(F)F

Computed descriptors from PubChem (CID 71577426), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.