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Chemical structure of GSK2850163 hydrochloride

GC34205

GSK2850163 hydrochloride

Also known as (5R)-2-[(3,4-dichlorophenyl)methyl]-N-[(4-methylphenyl)methyl]-2,7-diazaspiro[4.5]decane-7-carboxamide;hydrochloride

GSK2850163 hydrochloride is a novel inhibitor of inositol-requiring enzyme-1 alpha (IRE1α) which can inhibit IRE1α kinase activity and RNase activity with IC50s of 20 and 200 nM, respectively

ChemicalCAS2319838-09-8MW482.87FormulaC24H30Cl3N3O
CAS number
2319838-09-8
Molecular weight
482.87
Formula
C24H30Cl3N3O
Solubility
Soluble in DMSO
InChIKey
LVGWEPWHQGFBQD-GJFSDDNBSA-N
Catalogue number
GC34205
Brand
GLPBIO
Computed properties PubChem CID 132472232 · TPSA 35.6 Ų · H-bond donors 2 · H-bond acceptors 2
TPSA
35.6 Ų
H-bond donors
2
H-bond acceptors
2
Rotatable bonds
4
Heavy atoms
31

SMILES CC1=CC=C(C=C1)CNC(=O)N2CCC[C@@]3(C2)CCN(C3)CC4=CC(=C(C=C4)Cl)Cl.Cl

Computed descriptors from PubChem (CID 132472232), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.