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Chemical structure of JSH-150

GC34204

JSH-150

Also known as 4-[[[4-[5-chloro-2-[[4-(2-methoxyethylamino)cyclohexyl]amino]-4-pyridinyl]-1,3-thiazol-2-yl]amino]methyl]oxane-4-carbonitrile

JSH-150 is a highly selective and potent CDK9 inhibitor with an IC50 of 1 nM

ChemicalCAS2247481-21-4MW505.08FormulaC24H33ClN6O2S
CAS number
2247481-21-4
Molecular weight
505.08
Formula
C24H33ClN6O2S
Solubility
DMSO ： 16·67 mg/mL (33·00 mM)
InChIKey
XSDZPPRQLIZLDG-UHFFFAOYSA-N
Catalogue number
GC34204
Brand
GLPBIO
Computed properties PubChem CID 134814484 · XLogP 4 · TPSA 132 Ų · H-bond donors 3
XLogP
4
TPSA
132 Ų
H-bond donors
3
H-bond acceptors
9
Rotatable bonds
10
Heavy atoms
34

SMILES COCCNC1CCC(CC1)NC2=NC=C(C(=C2)C3=CSC(=N3)NCC4(CCOCC4)C#N)Cl

Computed descriptors from PubChem (CID 134814484), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.