GC34190
DC1-SMe
Also known as N-[2-[(1S)-1-(chloromethyl)-5-hydroxy-1,2-dihydrobenzo[e]indole-3-carbonyl]-1H-indol-5-yl]-5-[3-(methyldisulfanyl)propanoylamino]-1H-indole-2-carboxamide
DC1Sme, a DC1 derivative, exhibits IC50 values of 22 pM, 10 pM, 32 pM and 250 pM for Ramos, Namalwa, HL60/s and COLO 205 cancer cells, respectively· DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is a ADC Cytotoxin· DC1 can be used in synthesis of antibody-drug conjugates for the targeted treatment of cancer
- CAS number
- 501666-85-9
- Molecular weight
- 684.23
- Formula
- C35H30ClN5O4S2
- Solubility
- Soluble in DMSO
- InChIKey
- TVEHPTDUSKNJAT-OAQYLSRUSA-N
- Catalogue number
- GC34190
- Brand
- GLPBIO
Computed properties PubChem CID 10327248 · XLogP 5.8 · TPSA 181 Ų · H-bond donors 5
- XLogP
- 5.8
- TPSA
- 181 Ų
- H-bond donors
- 5
- H-bond acceptors
- 6
- Rotatable bonds
- 9
- Heavy atoms
- 47
SMILES CSSCCC(=O)NC1=CC2=C(C=C1)NC(=C2)C(=O)NC3=CC4=C(C=C3)NC(=C4)C(=O)N5C[C@H](C6=C5C=C(C7=CC=CC=C76)O)CCl
Computed descriptors from PubChem (CID 10327248), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il