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Chemical structure of Talabostat

GC33853

Talabostat

Also listed as Talabostat (PT100)

Talabostat (PT100) is an orally active and non-selective inhibitor of dipeptidyl peptidase IV (DPP-IV) (IC50 < 4 nM; Ki = 0·18 nM) and the first clinical inhibitor of fibroblast activation protein (FAP) (IC50= 560 nM), inhibiting DPP 8/9 (IC50= 4/11 nM; Ki = 1·5/0·76 nM), prolyl endopeptidase (QPP) (IC50= 310 nM), DPP2, and other DASH family enzymes

ChemicalCAS149682-77-9MW214.07FormulaC9H19BN2O3
CAS number
149682-77-9
Molecular weight
214.07
Formula
C9H19BN2O3
Solubility
DMSO ： ≥ 40 mg/mL (186·85 mM)
InChIKey
FKCMADOPPWWGNZ-YUMQZZPRSA-N
Catalogue number
GC33853
Brand
GLPBIO
Computed properties PubChem CID 6918572 · TPSA 86.8 Ų · H-bond donors 3 · H-bond acceptors 4
TPSA
86.8 Ų
H-bond donors
3
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
15

SMILES B([C@@H]1CCCN1C(=O)[C@H](C(C)C)N)(O)O

Computed descriptors from PubChem (CID 6918572), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.