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Chemical structure of Talabostat mesylate

GC10018

Talabostat mesylate

Also known as [(2R)-1-[(2S)-2-amino-3-methylbutanoyl]pyrrolidin-2-yl]boronic acid;methanesulfonic acid

Talabostat (PT100) is an orally active and non-selective inhibitor of dipeptidyl peptidase IV (DPP-IV) (IC50 < 4 nM; Ki = 0·18 nM) and the first clinical inhibitor of fibroblast activation protein (FAP) (IC50= 560 nM), inhibiting DPP 8/9 (IC50= 4/11 nM; Ki = 1·5/0·76 nM), prolyl endopeptidase (QPP) (IC50= 310 nM), DPP2, and other DASH family enzymes

ChemicalCAS150080-09-4MW310.18FormulaC10H23BN2O6S
CAS number
150080-09-4
Molecular weight
310.18
Formula
C10H23BN2O6S
Solubility
≥ 11·45mg/mL in DMSO
InChIKey
OXYYOEIGQRXGPI-WSZWBAFRSA-N
Catalogue number
GC10018
Brand
GLPBIO
Computed properties PubChem CID 11522448 · TPSA 150 Ų · H-bond donors 4 · H-bond acceptors 7
TPSA
150 Ų
H-bond donors
4
H-bond acceptors
7
Rotatable bonds
3
Heavy atoms
20

SMILES B([C@@H]1CCCN1C(=O)[C@H](C(C)C)N)(O)O.CS(=O)(=O)O

Computed descriptors from PubChem (CID 11522448), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.