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Chemical structure of JAK3-IN-7

GC33382

JAK3-IN-7

Also known as 3-[3-methyl-8-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,8-diazaspiro[3.5]nonan-1-yl]-3-oxopropanenitrile

JAK3-IN-7 is a potent and selective JAK3 inhibitor extracted from patent WO2011013785A1, has an IC50 of ＜0·01 μM

ChemicalCAS1263774-57-7MW324.38FormulaC17H20N6O
CAS number
1263774-57-7
Molecular weight
324.38
Formula
C17H20N6O
Solubility
Soluble in DMSO
InChIKey
YAGUGWDMCPHBFF-UHFFFAOYSA-N
Catalogue number
GC33382
Brand
GLPBIO
Computed properties PubChem CID 50913620 · XLogP 1.4 · TPSA 88.9 Ų · H-bond donors 1
XLogP
1.4
TPSA
88.9 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
2
Heavy atoms
24

SMILES CC1CN(C12CCCN(C2)C3=NC=NC4=C3C=CN4)C(=O)CC#N

Computed descriptors from PubChem (CID 50913620), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.