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Chemical structure of JNJ-38877618

GC33266

JNJ-38877618

Also known as 6-[difluoro-(6-pyridin-4-yl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]quinoline

JNJ-38877618 is a potent, highly selective, orally bioavailable Met kinase inhibitor with IC50s of 2 and 3 nM for wild type and mutant Met, respectively

ChemicalCAS943540-74-7MW374.35FormulaC20H12F2N6
CAS number
943540-74-7
Molecular weight
374.35
Formula
C20H12F2N6
Solubility
DMSO ： 5 mg/mL (13·36 mM)
InChIKey
KOAWAWHSMVKCON-UHFFFAOYSA-N
Catalogue number
GC33266
Brand
GLPBIO
Computed properties PubChem CID 57654476 · XLogP 2.7 · TPSA 68.9 Ų · H-bond donors 0
XLogP
2.7
TPSA
68.9 Ų
H-bond donors
0
H-bond acceptors
7
Rotatable bonds
3
Heavy atoms
28

SMILES C1=CC2=C(C=CC(=C2)C(C3=NN=C4N3N=C(C=C4)C5=CC=NC=C5)(F)F)N=C1

Computed descriptors from PubChem (CID 57654476), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.