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Chemical structure of MK2-IN-1 (MK2 Inhibitor)

GC33142

MK2-IN-1 (MK2 Inhibitor)

Also known as 5-(4-chlorophenyl)-N-(4-piperazin-1-ylphenyl)-N-(pyridin-2-ylmethyl)furan-2-carboxamide

MK2-IN-1 (MK2 Inhibitor) is a potent and selecitve MAPKAPK2(MK2) inhibitor(IC50=0·11 uM) with a non-ATP competitive binding mode

ChemicalCAS1314118-92-7MW472.97FormulaC27H25ClN4O2
CAS number
1314118-92-7
Molecular weight
472.97
Formula
C27H25ClN4O2
Solubility
Soluble in DMSO
InChIKey
LIPNXDIBECKOMJ-UHFFFAOYSA-N
Catalogue number
GC33142
Brand
GLPBIO
Computed properties PubChem CID 53475321 · XLogP 4.6 · TPSA 61.6 Ų · H-bond donors 1
XLogP
4.6
TPSA
61.6 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
6
Heavy atoms
34

SMILES C1CN(CCN1)C2=CC=C(C=C2)N(CC3=CC=CC=N3)C(=O)C4=CC=C(O4)C5=CC=C(C=C5)Cl

Computed descriptors from PubChem (CID 53475321), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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