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Chemical structure of MK2 Inhibitor IV

GC16723

MK2 Inhibitor IV

Also known as 5-(4-chlorophenyl)-N-(4-piperazin-1-ylphenyl)-N-(pyridin-2-ylmethyl)furan-2-carboxamide;hydrochloride

MK2 Inhibitor IV is a potent and selecitve MAPKAPK2(MK2) inhibitor(IC50=0·11 uM) with a non-ATP competitive binding mode

ChemicalCAS1314118-94-9MW509.4FormulaC27H25ClN4O2 • HCl
CAS number
1314118-94-9
Molecular weight
509.4
Formula
C27H25ClN4O2 • HCl
Solubility
<5·09mg/mL in DMSO
InChIKey
AZDOSXSDARWKGX-UHFFFAOYSA-N
Catalogue number
GC16723
Brand
GLPBIO
Computed properties PubChem CID 70681199 · TPSA 61.6 Ų · H-bond donors 2 · H-bond acceptors 5
TPSA
61.6 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
6
Heavy atoms
35

SMILES C1CN(CCN1)C2=CC=C(C=C2)N(CC3=CC=CC=N3)C(=O)C4=CC=C(O4)C5=CC=C(C=C5)Cl.Cl

Computed descriptors from PubChem (CID 70681199), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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Documents
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