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Chemical structure of BAY1238097

GC33104

BAY1238097

Also known as (4S)-7,8-dimethoxy-N,4-dimethyl-1-[4-(4-methylpiperazin-1-yl)phenyl]-4,5-dihydro-2,3-benzodiazepine-3-carboxamide

BAY1238097 is a potent and selective inhibitor of BET binding to histones and has strong anti-proliferative activity in different AML (acute myeloid leukemia) and MM (multiple myeloma) models through down-regulation of c-Myc levels and its downstream transcriptome (IC50 ＜100 nM)

ChemicalCAS1564268-08-1MW451.56FormulaC25H33N5O3
CAS number
1564268-08-1
Molecular weight
451.56
Formula
C25H33N5O3
Solubility
DMSO ： 150 mg/mL (332·18 mM)
InChIKey
CJIPEACKIJJYED-KRWDZBQOSA-N
Catalogue number
GC33104
Brand
GLPBIO
Computed properties PubChem CID 118237331 · XLogP 2.4 · TPSA 69.6 Ų · H-bond donors 1
XLogP
2.4
TPSA
69.6 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
33

SMILES C[C@H]1CC2=CC(=C(C=C2C(=NN1C(=O)NC)C3=CC=C(C=C3)N4CCN(CC4)C)OC)OC

Computed descriptors from PubChem (CID 118237331), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.