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Chemical structure of BAY1217389

GC19058

BAY1217389

Also known as N-cyclopropyl-4-[6-(2,3-difluoro-4-methoxyphenoxy)-8-(3,3,3-trifluoropropylamino)imidazo[1,2-b]pyridazin-3-yl]-2-methylbenzamide

BAY 1217389 is a potent, and selective inhibitor of the monopolar spindle 1 (MPS1) kinase with an IC50 value less than 10 nM

ChemicalCAS1554458-53-5MW561.5FormulaC27H24F5N5O3
CAS number
1554458-53-5
Molecular weight
561.5
Formula
C27H24F5N5O3
Solubility
DMSO ： ≥ 28 mg/mL (49·87 mM)
InChIKey
WNEILUNVMHVMPH-UHFFFAOYSA-N
Catalogue number
GC19058
Brand
GLPBIO
Computed properties PubChem CID 78320750 · XLogP 5.7 · TPSA 89.8 Ų · H-bond donors 2
XLogP
5.7
TPSA
89.8 Ų
H-bond donors
2
H-bond acceptors
11
Rotatable bonds
9
Heavy atoms
40

SMILES CC1=C(C=CC(=C1)C2=CN=C3N2N=C(C=C3NCCC(F)(F)F)OC4=C(C(=C(C=C4)OC)F)F)C(=O)NC5CC5

Computed descriptors from PubChem (CID 78320750), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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