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Chemical structure of TD-106

GC33068

TD-106

Also known as 3-(5-amino-4-oxo-1,2,3-benzotriazin-3-yl)piperidine-2,6-dione

TD-106 is a cereblon (CRBN) modulator, which can be used for targeted protein degradation· BRD4 PROTACs with TD-106 induce BRD4 degradation

ChemicalCAS2250288-69-6MW273.25FormulaC12H11N5O3
CAS number
2250288-69-6
Molecular weight
273.25
Formula
C12H11N5O3
Solubility
DMSO : ≥ 125 mg/mL (457·46 mM)
InChIKey
DXZBHVQOULDEPN-UHFFFAOYSA-N
Catalogue number
GC33068
Brand
GLPBIO
Computed properties PubChem CID 137628679 · XLogP 0.7 · TPSA 117 Ų · H-bond donors 2
XLogP
0.7
TPSA
117 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
1
Heavy atoms
20

SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C=CC=C3N=N2)N

Computed descriptors from PubChem (CID 137628679), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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