Loading...
Chemical structure of hVEGF-IN-1

GC32963

hVEGF-IN-1

Also known as N-[2-[4-[4-[2-(diethylamino)ethoxy]anilino]quinazolin-2-yl]phenyl]-3-(4-methylpiperazin-1-yl)propanamide

hVEGF-IN-1, a quinazoline derivative, could specifically bind to the G-rich sequence in the internal ribosome entry site A (IRES-A) and destabilize the G-quadruplex structure· hVEGF-IN-1 binds to the IRES-A (WT) with a Kd of 0·928 μM in SPR experiments· hVEGF-IN-1 could hinder tumor cells migration and repress tumor growth by decreasing VEGF-A protein expression

ChemicalCAS1637443-98-1MW581.75FormulaC34H43N7O2
CAS number
1637443-98-1
Molecular weight
581.75
Formula
C34H43N7O2
Solubility
DMSO ： 25 mg/mL (42·97 mM);Water ： ＜ 0·1 mg/mL (insoluble)
InChIKey
VIBJAHJNWHZSJP-UHFFFAOYSA-N
Catalogue number
GC32963
Brand
GLPBIO
Computed properties PubChem CID 131704486 · XLogP 4.8 · TPSA 85.9 Ų · H-bond donors 2
XLogP
4.8
TPSA
85.9 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
13
Heavy atoms
43

SMILES CCN(CC)CCOC1=CC=C(C=C1)NC2=NC(=NC3=CC=CC=C32)C4=CC=CC=C4NC(=O)CCN5CCN(CC5)C

Computed descriptors from PubChem (CID 131704486), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.