GC32946
PK11007
Also known as 5-chloro-2-methylsulfonylpyrimidine-4-carboxylic acid
PK11007 is a mild thiol alkylator with anticancer activity· PK11007 stabilizes p53 via selective alkylation of two surface-exposed cysteines without compromising its DNA binding activity· PK11007 induces mutant p53 cancer cell death by increasing reactive oxygen species (ROS) levels
ChemicalCAS38275-34-2MW236.63FormulaC6H5ClN2O4S
- CAS number
- 38275-34-2
- Molecular weight
- 236.63
- Formula
- C6H5ClN2O4S
- Solubility
- DMSO ： 100 mg/mL (422·60 mM)
- InChIKey
- WZUPWJVRWIVWEF-UHFFFAOYSA-N
- Catalogue number
- GC32946
- Brand
- GLPBIO
Computed properties PubChem CID 1241459 · XLogP 0.3 · TPSA 106 Ų · H-bond donors 1
- XLogP
- 0.3
- TPSA
- 106 Ų
- H-bond donors
- 1
- H-bond acceptors
- 6
- Rotatable bonds
- 2
- Heavy atoms
- 14
SMILES CS(=O)(=O)C1=NC=C(C(=N1)C(=O)O)Cl
Computed descriptors from PubChem (CID 1241459), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il