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Chemical structure of NMS-859

GC32874

NMS-859

Also known as 2-chloro-N-[3-[(1,1-dioxo-1,2-benzothiazol-3-yl)amino]phenyl]acetamide

NMS-859 is a potent, covalent VCP (p97) inhibitor, with IC50s of 0·37 and 0·36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively

ChemicalCAS1449236-96-7MW349.79FormulaC15H12ClN3O3S
CAS number
1449236-96-7
Molecular weight
349.79
Formula
C15H12ClN3O3S
Solubility
DMSO : ≥ 42 mg/mL (120·07 mM)
InChIKey
JWMFLBAPPIWNGG-UHFFFAOYSA-N
Catalogue number
GC32874
Brand
GLPBIO
Computed properties PubChem CID 71607189 · XLogP 1.8 · TPSA 96 Ų · H-bond donors 2
XLogP
1.8
TPSA
96 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
23

SMILES C1=CC=C2C(=C1)C(=NS2(=O)=O)NC3=CC(=CC=C3)NC(=O)CCl

Computed descriptors from PubChem (CID 71607189), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.