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Chemical structure of Pyrotinib

GC32733

Pyrotinib

Also listed as Pyrotinib (SHR-1258)

Pyrotinib (SHR-1258) (SHR-1258) is a potent and selective EGFR/HER2 dual inhibitor with IC50s of 13 and 38 nM, respectively

ChemicalCAS1269662-73-8MW583.08FormulaC32H31ClN6O3
CAS number
1269662-73-8
Molecular weight
583.08
Formula
C32H31ClN6O3
Solubility
DMSO ： 0·172 mg/mL (0·29 mM)
InChIKey
SADXACCFNXBCFY-IYNHSRRRSA-N
Catalogue number
GC32733
Brand
GLPBIO
Computed properties PubChem CID 51039030 · XLogP 5.4 · TPSA 112 Ų · H-bond donors 2
XLogP
5.4
TPSA
112 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
10
Heavy atoms
42

SMILES CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)/C=C/[C@H]5CCCN5C

Computed descriptors from PubChem (CID 51039030), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.