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Chemical structure of Forodesine Hydrochloride

GC32708

Forodesine Hydrochloride

Also listed as Forodesine hydrochloride (BCX-1777)

Forodesine hydrochloride (BCX-1777) (BCX-1777 hydrochloride) is a highly potent and orally active purine nucleoside phosphorylase (PNP) inhibitor with IC50 values ranging from 0·48 to 1·57 nM for human, mouse, rat, monkey and dog PNP· Forodesine hydrochloride (BCX-1777) is a potent human lymphocyte proliferation inhibitor· Forodesine hydrochloride (BCX-1777) could induce apoptosis in leukemic cells by increasing the dGTP levels

ChemicalCAS284490-13-7MW302.71FormulaC11H15ClN4O4
CAS number
284490-13-7
Molecular weight
302.71
Formula
C11H15ClN4O4
Solubility
Water ： ≥ 74·1 mg/mL (244·79 mM)
InChIKey
WEIAMZKHBCLFOG-QPAIBFMUSA-N
Catalogue number
GC32708
Brand
GLPBIO
Computed properties PubChem CID 135449327 · TPSA 130 Ų · H-bond donors 7 · H-bond acceptors 6
TPSA
130 Ų
H-bond donors
7
H-bond acceptors
6
Rotatable bonds
2
Heavy atoms
20

SMILES C1=C(C2=C(N1)C(=O)NC=N2)[C@H]3[C@@H]([C@@H]([C@H](N3)CO)O)O.Cl

Computed descriptors from PubChem (CID 135449327), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.