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Chemical structure of Pralsetinib

GC31780

Pralsetinib

Also listed as Pralsetinib (Blu667)

Pralsetinib (Blu667) (BLU-667) is a highly potent, selective RET inhibitor· Pralsetinib (Blu667) (BLU-667) inhibits WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion with IC50s of 0·4, 0·3, 0·4, 0·4, and 0·4 nM, respectively

ChemicalCAS2097132-94-8MW533.6FormulaC27H32FN9O2
CAS number
2097132-94-8
Molecular weight
533.6
Formula
C27H32FN9O2
Solubility
DMSO ： ≥ 100 mg/mL (187·41 mM);Water ： ＜ 0·1 mg/mL (insoluble)
InChIKey
GBLBJPZSROAGMF-SIYOEGHHSA-N
Catalogue number
GC31780
Brand
GLPBIO
Computed properties PubChem CID 129073603 · XLogP 3.1 · TPSA 136 Ų · H-bond donors 3
XLogP
3.1
TPSA
136 Ų
H-bond donors
3
H-bond acceptors
9
Rotatable bonds
8
Heavy atoms
39

SMILES CC1=CC(=NN1)NC2=NC(=NC(=C2)C)C3CCC(CC3)(C(=O)N[C@@H](C)C4=CN=C(C=C4)N5C=C(C=N5)F)OC

Computed descriptors from PubChem (CID 129073603), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.