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Chemical structure of (Melle-4)cyclosporin

GC31646

(Melle-4)cyclosporin

Also listed as NIM811 ((Melle-4)cyclosporin)

NIM811 ((Melle-4)cyclosporin) ((Melle-4)cyclosporin; SDZ NIM811 ((Melle-4)cyclosporin)) is an orally bioavailable mitochondrial permeability transition and cyclophilin dual inhibitor, which exhibits potent in vitro activity against hepatitis C virus (HCV)

ChemicalCAS143205-42-9MW1202.61FormulaC62H111N11O12
CAS number
143205-42-9
Molecular weight
1202.61
Formula
C62H111N11O12
Solubility
DMSO ： ≥ 100 mg/mL (83·15 mM);Water ： ＜ 0·1 mg/mL (insoluble)
InChIKey
RPJPZDVUUKWPGT-FOIHOXPVSA-N
Catalogue number
GC31646
Brand
GLPBIO
Computed properties PubChem CID 6473876 · XLogP 7.5 · TPSA 279 Ų · H-bond donors 5
XLogP
7.5
TPSA
279 Ų
H-bond donors
5
H-bond acceptors
12
Rotatable bonds
15
Heavy atoms
85

SMILES CC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)[C@@H](C)CC)C)C

Computed descriptors from PubChem (CID 6473876), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.