GC71149
NIC-0102
Also known as [(1R)-1-[[(2S)-2-[(2,6-difluorobenzoyl)amino]-3-phenylpropanoyl]amino]-3-methylbutyl]boronic acid
NIC-0102 is an orally active proteasome inhibitor (pIC50=7·55) that specifically inhibits NLRP3 inflammatory vesicle activation
ChemicalCAS2806031-94-5MW418.24FormulaC21H25BF2N2O4
- CAS number
- 2806031-94-5
- Molecular weight
- 418.24
- Formula
- C21H25BF2N2O4
- Solubility
- DMSO ： 100 mg/mL (239·10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
- InChIKey
- QTRFWSIBLJYXFJ-ROUUACIJSA-N
- Catalogue number
- GC71149
- Brand
- GLPBIO
Computed properties PubChem CID 164946740 · TPSA 98.7 Ų · H-bond donors 4 · H-bond acceptors 6
- TPSA
- 98.7 Ų
- H-bond donors
- 4
- H-bond acceptors
- 6
- Rotatable bonds
- 9
- Heavy atoms
- 30
SMILES B([C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=C(C=CC=C2F)F)(O)O
Computed descriptors from PubChem (CID 164946740), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il